SwePub
Tyck till om SwePub Sök här!
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Stone Donald U.)
 

Sökning: WFRF:(Stone Donald U.) > Gottenberg Jacques Eric > Rare X Chromosome A...

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjogrens Syndrome

Sharma, Rohan (författare)
University of Oklahoma, OK USA; Department Vet Affairs Medical Centre, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma Med Res Fdn, Oklahoma City, OK USA.;Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
Harris, Valerie M. (författare)
Oklahoma Medical Research Fdn, OK 73104 USA; University of Oklahoma, OK USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.;Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Cavett, Joshua (författare)
Oklahoma Medical Research Fdn, OK 73104 USA; University of Oklahoma, OK USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.;Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
visa fler...
Kurien, Biji T. (författare)
University of Oklahoma, OK USA; Department Vet Affairs Medical Centre, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma Med Res Fdn, Oklahoma City, OK USA.;Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
Liu, Ke (författare)
Cincinnati Childrens Hospital Medical Centre, OH 45229 USA; University of Cincinnati, OH USA,Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA.;Univ Cincinnati, Cincinnati, OH USA.
Koelsch, Kristi A. (författare)
University of Oklahoma, OK USA; Department Vet Affairs Medical Centre, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma Med Res Fdn, Oklahoma City, OK USA.;Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
Fayaaz, Anum (författare)
Department Vet Affairs Medical Centre, OK USA,Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
Chaudhari, Kaustubh S. (författare)
Department Vet Affairs Medical Centre, OK USA,Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
Radfar, Lida (författare)
University of Oklahoma, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Lewis, David (författare)
University of Oklahoma, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Stone, Donald U. (författare)
Johns Hopkins University, MD USA; King Khalid Eye Specialist Hospital, Saudi Arabia,Johns Hopkins Univ, Baltimore, MD USA.;King Khalid Eye Specialist Hosp, Riyadh, Saudi Arabia.
Erick Kaufman, C. (författare)
University of Oklahoma, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Li, Shibo (författare)
University of Oklahoma, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Segal, Barbara (författare)
University of Minnesota, MN 55455 USA,Univ Minnesota, Sch Med, Minneapolis, MN 55455 USA.
Wallace, Daniel J. (författare)
Cedars Sinai Medical Centre, CA 90048 USA,Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA.
Weisman, Michael H. (författare)
Cedars Sinai Medical Centre, CA 90048 USA
Venuturupalli, Swamy (författare)
Cedars Sinai Medical Centre, CA 90048 USA,Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA.
Kelly, Jennifer A. (författare)
Oklahoma Medical Research Fdn, OK 73104 USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.
Pons-Estel, Bernardo (författare)
Sanatorio Parque, Rosario, Argentina.
Jonsson, Roland (författare)
University of Bergen, Norway; Haukeland Hospital, Norway,Univ Bergen, Bergen, Norway.;Haukeland Hosp, Bergen, Norway.
Lu, Xianglan (författare)
University of Oklahoma, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Gottenberg, Jacques-Eric (författare)
Strasbourg University, France,Strasbourg Univ, Strasbourg, France.
Anaya, Juan-Manuel (författare)
University of Rosario, Colombia,Univ Rosario, Bogota, Colombia.
Cunninghame-Graham, Deborah S. (författare)
Kings Coll London, London, England.
Huang, Andrew J. W. (författare)
University of Minnesota, MN USA,Univ Minnesota, Minneapolis, MN USA.
Brennan, Michael T. (författare)
Carolinas Medical Centre, NC 28203 USA,Carolinas Med Ctr, Charlotte, NC 28203 USA.
Hughes, Pamela (författare)
University of Minnesota, MN USA,Univ Minnesota, Minneapolis, MN USA.
Alevizos, Ilias (författare)
National Institute Dent and Craniofacial Research, MD USA,Natl Inst Dent & Craniofacial Res, NIH, Bethesda, MD USA.
Miceli-Richard, Corinne (författare)
University of Paris Sud, France,Univ Paris Sud, AP HP, Dept Rheumatol, INSERM,U1012, Le Kremlin Bicetre, France.
Keystone, Edward C. (författare)
Mt Sinai Hospital, Canada; University of Toronto, Canada,Mt Sinai Hosp, Toronto, ON, Canada.;Univ Toronto, Toronto, ON, Canada.
Bykerk, Vivian P. (författare)
Hospital Special Surg, NY 10021 USA,Hosp Special Surg, 535 E 70th St, New York, NY 10021 USA.
Hirschfield, Gideon (författare)
University of Birmingham, England,Univ Birmingham, Birmingham, W Midlands, England.
Nordmark, Gunnel (författare)
Uppsala universitet,Reumatologi,Uppsala University, Sweden
Magnusson Bucher, Sara (författare)
Örebro University Hospital, Sweden,Orebro Univ Hosp, Orebro, Sweden.
Eriksson, Per (författare)
Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Reumatologiska kliniken i Östergötland,Linkoping Univ, Linkoping, Sweden.
Omdal, Roald (författare)
Stavanger University Hospital, Norway,Stavanger Univ Hosp, Stavanger, Norway.
Rhodus, Nelson L. (författare)
University of Minnesota, MN USA,Univ Minnesota, Minneapolis, MN USA.
Rischmueller, Maureen (författare)
Queen Elizabeth Hospital, Australia; University of Adelaide, Australia,Queen Elizabeth Hosp, Woodville South, SA, Australia.;Univ Adelaide, Adelaide, SA, Australia.
Rohrer, Michael (författare)
University of Minnesota, MN USA,Univ Minnesota, Minneapolis, MN USA.
Wahren-Herlenius, Marie (författare)
Karolinska Institutet
Witte, Torsten (författare)
Hannover Medical Sch, Germany,Hannover Med Sch, Hannover, Germany.
Alarcon-Riquelme, Marta (författare)
Karolinska Institutet
Mariette, Xavier (författare)
University of Paris Sud, France,Univ Paris Sud, AP HP, Dept Rheumatol, INSERM,U1012, Le Kremlin Bicetre, France.
Lessard, Christopher J. (författare)
Oklahoma Medical Research Fdn, OK 73104 USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.
Harley, John B. (författare)
University of Cincinnati, OH USA; Ohio Department Vet Affairs Medical Centre, OH USA,Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH USA.;Ohio Dept Vet Affairs Med Ctr, Cincinnati, OH USA.
Ng, Wan-Fai (författare)
Newcastle University, England,Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England.
Rasmussen, Astrid (författare)
Oklahoma Medical Research Fdn, OK 73104 USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.
Sivils, Kathy L. (författare)
Oklahoma Medical Research Fdn, OK 73104 USA; University of Oklahoma, OK USA,Oklahoma Med Res Fdn, 825 NE 13th St, Oklahoma City, OK 73104 USA.;Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA.
Hal Scofield, R. (författare)
University of Oklahoma, OK USA; Department Vet Affairs Medical Centre, OK USA,Univ Oklahoma, Hlth Sci Ctr, Oklahoma Med Res Fdn, Oklahoma City, OK USA.;Dept Vet Affairs Med Ctr, Oklahoma City, OK USA.
visa färre...
University of Oklahoma, OK USA; Department Vet Affairs Medical Centre, OK USA Univ Oklahoma, Hlth Sci Ctr, Oklahoma Med Res Fdn, Oklahoma City, OK USA;Dept Vet Affairs Med Ctr, Oklahoma City, OK USA. (creator_code:org_t)
2017-10-12
2017
Engelska.
Ingår i: Arthritis & Rheumatology. - : WILEY. - 2326-5191 .- 2326-5205. ; 69:11, s. 2187-2192
Relaterad länk:
http://pure-oai.bham...
visa fler...
https://urn.kb.se/re...
https://doi.org/10.1...
https://urn.kb.se/re...
http://kipublication...
visa färre...
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objective. Sjogrens syndrome (SS) and systemic lupus erythematosus (SLE) are related by clinical and serologic manifestations as well as genetic risks. Both diseases are more commonly found in women than in men, at a ratio of similar to 10 to 1. Common X chromosome aneuploidies, 47,XXY and 47,XXX, are enriched among men and women, respectively, in either disease, suggesting a dose effect on the X chromosome. Methods. We examined cohorts of SS and SLE patients by constructing intensity plots of X chromosome single-nucleotide polymorphism alleles, along with determining the karyotype of selected patients. Results. Among similar to 2,500 women with SLE, we found 3 patients with a triple mosaic, consisting of 45,X/46,XX/47,XXX. Among similar to 2,100 women with SS, 1 patient had 45,X/46,XX/47,XXX, with a triplication of the distal p arm of the X chromosome in the 47,XXX cells. Neither the triple mosaic nor the partial triplication was found among the controls. In another SS cohort, we found a mother/daughter pair with partial triplication of this same region of the X chromosome. The triple mosaic occurs in similar to 1 in 25,000-50,000 live female births, while partial triplications are even rarer. Conclusion. Very rare X chromosome abnormalities are present among patients with either SS or SLE and may inform the location of a gene(s) that mediates an X dose effect, as well as critical cell types in which such an effect is operative.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy